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DU4L7 Rabbit Polyclonal Antibody, 50ul Protein Research |Belongs to the integrin alpha

SKU: 27477883421

4.3
PLN162.00 PLN198.00

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DU4L7 Rabbit Polyclonal Antibody, 50ul Protein Research |Belongs to the integrin alphaThis gene is located within a D4Z4 repeat array in the subtelomeric region of chromosome 4q. The D4Z4 repeat is polymorphic in length and a similar D4Z4 repeat array has been identified on chromosome 10. Each D4Z4 repeat unit has an open reading frame (named DUX4) that encodes two homeoboxes; the repeat array and ORF is conserved in other mammals. There is no evidence for transcription of the gene at this locus though RT PCR and in vitro expression

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Description

|Belongs to the integrin alpha chain family

The protein encoded by this gene is a member of the FG-repeat containing nucleoporins and is localized to the nuclear pore central plug

Inhibition of inositol monophosphate hydroylosis and subsequent depletion of inositol for phosphatidylinositol synthesis may explain the anti-manic and anti-depressive effects of lithium administered to treat bipolar disorder

BPTI/Kunitz inhibitor and E2 domains in the middle region

This protein may tightly associate or interact with the pyruvate dehydrogenase complex

DU4L7 Rabbit Polyclonal Antibody, 50ul Protein Research |Belongs to the integrin alphaThis gene is located within a D4Z4 repeat array in the subtelomeric region of chromosome 4q. The D4Z4 repeat is polymorphic in length and a similar D4Z4 repeat array has been identified on chromosome 10. Each D4Z4 repeat unit has an open reading frame (named DUX4) that encodes two homeoboxes; the repeat array and ORF is conserved in other mammals. There is no evidence for transcription of the gene at this locus though RT PCR and in vitro expression

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