SPZ1 Polyclonal Antibody, 50ul Insect Expression They associate with Kv4 alpha

They associate with Kv4 alpha subunits to form native Kv4 channel complexes

A unique region of this protein has also been shown to be involved in the regulation of lysosomal morphology

2004 [PubMed 15150103])

Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized

PER3 is upregulated by CLOCK/ARNTL heterodimers but then represses this upregulation in a feedback loop using PER/CRY heterodimers to interact with CLOCK/ARNTL

SPZ1 Polyclonal Antibody, 50ul Insect Expression They associate with Kv4 alphaSPZ1 (spermatogenic leucine zipper 1) encodes a bHLH zip transcription factor which functions in the mitogen activate protein kinase (MAPK) signaling pathway. Because of its role in the upregulation of cell proliferation and tumorigenesis, SPZ1 may serve as a target for Ras induced tumor treatments.