Histone deacetylase 6 Polyclonal Antibody, 100ul Pipette Holder Activity of voltage-gated potassium channels

Activity of voltage-gated potassium channels is important in a number of physiological processes

Defects in this gene have been reported to cause spastic paraplegia autosomal dominant type 42 (SPG42) in one Chinese family| but not in similar patients of European descent

Mutations in the gene cause Sjogren-Larsson syndrome

which are composed of four subunits and function as ligand-activated ion channels

The long form is expressed in steroidogenic tissues such as testis

Histone deacetylase 6 Polyclonal Antibody, 100ul Pipette Holder Activity of voltage-gated potassium channelsHistones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation deacetylation alters chromosome structure and affects transcription factor access to DNA. Histone deacetylase 6 encoded by HDAC6 belongs to class II of the histone deacetylase acuc apha family. It contains an internal duplication of two catalytic domains which appear to function independently of each other. This protein