MDMX(Phospho Ser367) Polyclonal Antibody, 100ul Pipette Controller It is a tetramer composed

It is a tetramer composed of 1 alpha| 1 beta| and 2 gamma chains

Downregulation of expression of this gene by promoter hypermethylation has been observed in a wide spectrum of human malignancies

PHAX contains a conserved single-stranded nucleic acid binding domain (RNA_GG_bind domain) with no sequence homology with any other known RNA-binding module [PMID: 15574332

It interacts with and accelerates the opening of the mitochondrial voltage-dependent anion channel

PRKD1 is a serine/threonine kinase that regulates a variety of cellular functions

MDMX(Phospho Ser367) Polyclonal Antibody, 100ul Pipette Controller It is a tetramer composedThis gene encodes a nuclear protein that contains a p53 binding domain at the N terminus and a RING finger domain at the C terminus, and shows structural similarity to p53 binding protein MDM2. Both proteins bind the p53 tumor suppressor protein and inhibit its activity, and have been shown to be overexpressed in a variety of human cancers. However, unlike MDM2 which degrades p53, this protein inhibits p53 by binding its transcriptional activation