Stat5 Polyclonal Antibody, 20ul[BT-AP08635] Protein Post-translational Modification Alternative splicing of SRPK1 results

Alternative splicing of SRPK1 results in multiple transcript variants

the alpha2A subtype inhibited transmitter release at high stimulation frequencies

STE20-related kinase adapter protein alpha encoded by STRADA contains a STE20-like kinase domain

Variations in the number of 23 amino acid repeats in the neck domain of this protein are rare but have a significant impact on ligand binding ability

possibly as a result of compromised regulatory T cell recruitment

Stat5 Polyclonal Antibody, 20ul[BT-AP08635] Protein Post-translational Modification Alternative splicing of SRPK1 resultsStat5 is activated in response to a wide variety of ligands including IL 2, GM CSF, growth hormone and prolactin. Phosphorylation at Tyr694 is obligatory for Stat5 activation. This phosphorylation is mediated by Src upon erythropoietin stimulation. Stat5 is constitutively active in some leukemic cell types. Phosphorylated Stat5 is found in some endothelial cells treated with IL 3, which suggests its involvement in angiogenesis and cell motility.