SRBS2 Rabbit Polyclonal Antibody, 100ul Serum & Sample Tubes Tyrosine protein kinases are important

Tyrosine protein kinases are important regulators of intracellular signal transduction pathways| mediating cellular proliferation| survival| and development

Alternative splicing results in multiple transcript variants| some of which encode distinct isoforms| including a protease packaged into dense core granules (PC5A) and a type 1 membrane bound protease (PC5B)

has been associated with deletions of chromosome 22q11

where they appear to provide protective functions

The P1 downstream promoter of this gene is imprinted

SRBS2 Rabbit Polyclonal Antibody, 100ul Serum & Sample Tubes Tyrosine protein kinases are importantArg and c Abl represent the mammalian members of the Abelson family of non receptor protein tyrosine kinases. They interact with the Arg Abl binding proteins via the SH3 domains present in the carboxy end of the latter group of proteins. This gene encodes the sorbin and SH3 domain containing 2 protein. It has three C terminal SH3 domains and an N terminal sorbin homology (SoHo) domain that interacts with lipid raft proteins. The subcellular