Plasminogen Polyclonal Antibody, 20ul Low retention tips two of which encode structurally

two of which encode structurally related isoforms known to function as inhibitors of CDK4 kinase

The subunit encoded by this gene is a large scaffolding protein that contains binding sites for other members of the EIF4F complex

DEFA4 differs from other genes of this family by an extra 83-base segment that is apparently the result of a recent duplication within the coding region

The encoded protein may be a tumor suppressor protein for melanoma

The level of mRNAs for this gene peaks in the G1 phase of the cell cycle

Plasminogen Polyclonal Antibody, 20ul Low retention tips two of which encode structurallyThe protein encoded by PLG (plasminogen) is a secreted blood zymogen that is activated by proteolysis and converted to plasmin and angiostatin. Plasmin dissolves fibrin in blood clots and is an important protease in many other cellular processes while angiostatin inhibits angiogenesis. Defects in PLG are likely a cause of thrombophilia and ligneous conjunctivitis. Two transcript variants encoding different isoforms have been found for PLG.