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GASP-1 Polyclonal Antibody, 50ul High Speed Micro-Centrifuges The protein is an integral

SKU: 23498902063

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GASP-1 Polyclonal Antibody, 50ul High Speed Micro-Centrifuges The protein is an integralGPRASP1 (G protein coupled receptor associated sorting protein 1) encodes a member of the GPRASP (G protein coupled receptor associated sorting protein) family. The protein may modulate lysosomal sorting and functional down regulation of a variety of G protein coupled receptors. It targets receptors for degradation in lysosomes. The receptors interacting with this sorting protein include D2 dopamine receptor (DRD2), delta opioid receptor (OPRD1), beta

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Description

The protein is an integral membrane protein and is one of the entry cofactors for hepatitis C virus

The encoded protein is found in an inactive cytoplasmic form that upon serine/threonine phosphorylation forms a complex with CREBBP

Three members of this gene family have been studied in detail and are estimated to generate over 3000 variants through the use of two alternative promoters (alpha and beta) and extensive alternative splicing in each family member

When translation ends upstream from the last exon-exon junction| this triggers NMD to degrade mRNAs containing premature stop codons

The protein encoded by this gene binds nucleosomal DNA and is associated with transcriptionally active chromatin

GASP-1 Polyclonal Antibody, 50ul High Speed Micro-Centrifuges The protein is an integralGPRASP1 (G protein coupled receptor associated sorting protein 1) encodes a member of the GPRASP (G protein coupled receptor associated sorting protein) family. The protein may modulate lysosomal sorting and functional down regulation of a variety of G protein coupled receptors. It targets receptors for degradation in lysosomes. The receptors interacting with this sorting protein include D2 dopamine receptor (DRD2), delta opioid receptor (OPRD1), beta

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