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PAK alpha/beta / gamma(Phospho Thr423/402/421) Polyclonal Antibody, 100ul DNA Fragments This gene encodes the rate-limiting

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PAK alpha/beta / gamma(Phospho Thr423/402/421) Polyclonal Antibody, 100ul DNA Fragments This gene encodes the rate-limitingThis gene encodes a family member of serine threonine p21 activating kinases, known as PAK proteins. These proteins are critical effectors that link RhoGTPases to cytoskeleton reorganization and nuclear signaling, and they serve as targets for the small GTP binding proteins Cdc42 and Rac. This specific family member regulates cell motility and morphology. Alternatively spliced transcript variants encoding different isoforms have been found for this

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Description

This gene encodes the rate-limiting enzyme of the polyamine biosynthesis pathway which catalyzes ornithine to putrescine

establishing its role in vascular disease

The antibody recognizes all the isoform of KIAA0100

The processed form is active and the unprocessed form acts as an inhibitor (I kappa B-like)| being able to form cytosolic complexes with NF-kappa B| trapping it in the cytoplasm

cell proliferation and pathological response

PAK alpha/beta / gamma(Phospho Thr423/402/421) Polyclonal Antibody, 100ul DNA Fragments This gene encodes the rate-limitingThis gene encodes a family member of serine threonine p21 activating kinases, known as PAK proteins. These proteins are critical effectors that link RhoGTPases to cytoskeleton reorganization and nuclear signaling, and they serve as targets for the small GTP binding proteins Cdc42 and Rac. This specific family member regulates cell motility and morphology. Alternatively spliced transcript variants encoding different isoforms have been found for this

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