DCMC Rabbit Polyclonal Antibody, 20ul Custom DNA Oligos ADCK4 and ADCK5

ADCK4 and ADCK5

TNF receptor superfamily member 10a encoded by TNFRSF10A is a member of the TNF-receptor superfamily

This gene appears to represent an intronless retrocopy of a related multi-exon gene located on chromosome 9

1 and one at chromosome 11p11

It is located close to translocation breakpoints associated with premature ovarian failure

DCMC Rabbit Polyclonal Antibody, 20ul Custom DNA Oligos ADCK4 and ADCK5The product of this gene catalyzes the breakdown of malonyl CoA to acetyl CoA and carbon dioxide. Malonyl CoA is an intermediate in fatty acid biosynthesis and also inhibits the transport of fatty acyl CoAs into mitochondria. Consequently the encoded protein acts to increase the rate of fatty acid oxidation. It is found in mitochondria peroxisomes and the cytoplasm. Mutations in this gene result in malonyl CoA decarboyxlase deficiency.