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Autotaxin Polyclonal Antibody, 100ul NGS Oligos The protein encoded by this

SKU: 23037472081

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Autotaxin Polyclonal Antibody, 100ul NGS Oligos The protein encoded by thisEctonucleotide pyrophosphatase phosphodiesterase family member 2 encoded by ENPP2 functions as both a phosphodiesterase, which cleaves phosphodiester bonds at the 5' end of oligonucleotides, and a phospholipase, which catalyzes production of lysophosphatidic acid (LPA) in extracellular fluids. LPA evokes growth factor like responses including stimulation of cell proliferation and chemotaxis. This gene product stimulates the motility of tumor cells and

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Description

The protein encoded by this gene is a small Rho GTPase and a candidate tumor suppressor

Smad proteins are phosphorylated and activated by transmembrane serine-threonine receptor kinases in response to TGF-beta signaling

An important paralog of this gene is TCEAL4

Defects in this gene have been associated with non-syndromic sensorineural deafness autosomal dominant type 17

At least two alternative splice variants encoding different protein isoforms have been described for this gene

Autotaxin Polyclonal Antibody, 100ul NGS Oligos The protein encoded by thisEctonucleotide pyrophosphatase phosphodiesterase family member 2 encoded by ENPP2 functions as both a phosphodiesterase, which cleaves phosphodiester bonds at the 5' end of oligonucleotides, and a phospholipase, which catalyzes production of lysophosphatidic acid (LPA) in extracellular fluids. LPA evokes growth factor like responses including stimulation of cell proliferation and chemotaxis. This gene product stimulates the motility of tumor cells and

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