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p53 (Acetyl-K120) Polyclonal Antibody, 50ul Culture Plate Inserts Acts as a transcriptional coactivator

SKU: 22524951583

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p53 (Acetyl-K120) Polyclonal Antibody, 50ul Culture Plate Inserts Acts as a transcriptional coactivatorThis gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li Fraumeni syndrome.

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Description

Acts as a transcriptional coactivator of serum response factor (SRF)

and this down-regulation may be an early and sensitive marker for the onset of transformation

Desmogleins

GRM7 and GRM8

Three members of this protein family (Ikaros

p53 (Acetyl-K120) Polyclonal Antibody, 50ul Culture Plate Inserts Acts as a transcriptional coactivatorThis gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li Fraumeni syndrome.

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