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BACE(Phospho Ser498) Rabbit Polyclonal Antibody, 20ul Vacuum Filter Unlike most mitochondrial matrix proteins

SKU: 22364267407

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BACE(Phospho Ser498) Rabbit Polyclonal Antibody, 20ul Vacuum Filter Unlike most mitochondrial matrix proteinsThis gene encodes a member of the peptidase A1 family of aspartic proteases. Alternative splicing results in multiple transcript variants at least one of which encodes a preproprotein that is proteolytically processed to generate the mature protease. This transmembrane protease catalyzes the first step in the formation of amyloid beta peptide from amyloid precursor protein. Amyloid beta peptides are the main constituent of amyloid beta plaques which

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Description

Unlike most mitochondrial matrix proteins

and the accumulation of insoluble dipeptide repeat protein aggregates that could be pathogenic in FTD-ALS patients (PMID: 23393093)

This gene encodes a member of a family of enzymes that function to add glutathione to target electrophilic compounds

Ideal for use in scientific and laboratory settings

The protein encoded by this gene phosphorylates the inhibitor in the inhibitor/NF-kappa-B complex| causing dissociation of the inhibitor and activation of NF-kappa-B

BACE(Phospho Ser498) Rabbit Polyclonal Antibody, 20ul Vacuum Filter Unlike most mitochondrial matrix proteinsThis gene encodes a member of the peptidase A1 family of aspartic proteases. Alternative splicing results in multiple transcript variants at least one of which encodes a preproprotein that is proteolytically processed to generate the mature protease. This transmembrane protease catalyzes the first step in the formation of amyloid beta peptide from amyloid precursor protein. Amyloid beta peptides are the main constituent of amyloid beta plaques which

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