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POLR3B Polyclonal Antibody, 100ul Capsule Filter Alternative splicing results in multiple

SKU: 22223301169

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POLR3B Polyclonal Antibody, 100ul Capsule Filter Alternative splicing results in multiplePOLR3B (RNA polymerase III subunit B) encodes the second largest subunit of RNA polymerase III, the polymerase responsible for synthesizing transfer and small ribosomal RNAs in eukaryotes. The largest subunit and the encoded protein form the catalytic center of RNA polymerase III. Mutations in this gene are a cause of hypomyelinating leukodystrophy. Alternatively spliced transcript variants encoding multiple isoforms have been observed for POLR3B.

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Description

Alternative splicing results in multiple transcript variants encoding identical proteins

where they help anchor the myofibrillar actin filaments

Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene| and a pseudogene of this gene is located on the long arm of chromosome 19

compared to isoform a

tissue specificity:Most abundant expression in the heart and pancreas

POLR3B Polyclonal Antibody, 100ul Capsule Filter Alternative splicing results in multiplePOLR3B (RNA polymerase III subunit B) encodes the second largest subunit of RNA polymerase III, the polymerase responsible for synthesizing transfer and small ribosomal RNAs in eukaryotes. The largest subunit and the encoded protein form the catalytic center of RNA polymerase III. Mutations in this gene are a cause of hypomyelinating leukodystrophy. Alternatively spliced transcript variants encoding multiple isoforms have been observed for POLR3B.

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