IPP-2(Phospho Ser120/S121) Polyclonal Antibody, 50ul Cell Labeling & Imaging Thought to stabilize the calcium

Thought to stabilize the calcium channel in an inactivated (closed) state

Catalytic activity:Strict requirement for Asp at the P1 position

Phosphorylated on upon DNA damage| probably by ATM or ATR

This gene encodes an integral membrane protein that is required for cytokine-induced regulation of the tight junction paracellular permeability barrier

Because of its increase due to acute inflammation| this protein is classified as an acute-phase reactant

IPP-2(Phospho Ser120/S121) Polyclonal Antibody, 50ul Cell Labeling & Imaging Thought to stabilize the calciumProtein phosphatase 1 (PP1) is one of the main eukaryotic serine threonine phosphatases. The protein encoded by this gene binds to the catalytic subunit of PP1, strongly inhibiting its activity. Ten related pseudogenes have been found throughout the human genome. Several splice variants encoding different isoforms have been found for this gene.