Rat Neuropilin-2, NRP2 ELISA Kit, 96T Sample Library Tubes extracellular ligands include parathyroid horomones

extracellular ligands include parathyroid horomones and the morphogen sonic hedgehog while cytosolic ligands include MAP kinase scaffold proteins and JNK interacting proteins

Also regulates epithelial to mesenchymal transition through a SMAD-independent signaling pathway through PARD6A phosphorylation and activation (By similarity)

Acts as a bona fide target gene of p53/TP53

Exhibits an extremely wide ligand pocket (By similarity)

Interacts directly with G-protein alpha subunits and can functionally regulate their activity (By similarity)

Rat Neuropilin-2, NRP2 ELISA Kit, 96T Sample Library Tubes extracellular ligands include parathyroid horomonesHigh affinity receptor for semaphorins 3C, 3F, VEGF 165 and VEGF 145 isoforms of VEGF, and the PLGF 2 isoform of PGF.