Nibrin Polyclonal Antibody, 100ul[BT-AP06022] Syringe Filter This gene forms the basis

This gene forms the basis for the Kidd blood group system

and may constitute a subfamily of the DOK genes

targeting the integrin for internalization and degradation

and bladder cancer

The encoded protein plays a role in the targeted trafficking of integrins via its association with integrin alpha tails

Nibrin Polyclonal Antibody, 100ul[BT-AP06022] Syringe Filter This gene forms the basisMutations in NBN are associated with Nijmegen breakage syndrome, an autosomal recessive chromosomal instability syndrome characterized by microcephaly, growth retardation, immunodeficiency, and cancer predisposition. Nibrin is a member of the MRE11 RAD50 double strand break repair complex which consists of 5 proteins. NBN product is thought to be involved in DNA double strand break repair and DNA damage induced checkpoint activation.