DNA Ligase IV Polyclonal Antibody, 50ul[BT-AP02653] Pipette Holder At least two transcript variants

At least two transcript variants encoding the same protein have been found for ATXN1 (ataxin 1)

Pseudogenes of this gene are located on the long arm of chromosomes 11 and 17

The encoded protein functions in part by phosphorylating members of the mitotic checkpoint complex and activating the spindle checkpoint

share a RAS association (RA) domain

also named as C21orf108

DNA Ligase IV Polyclonal Antibody, 50ul[BT-AP02653] Pipette Holder At least two transcript variantsThe protein encoded by LIG4 is a DNA ligase that joins single strand breaks in a double stranded polydeoxynucleotide in an ATP dependent reaction. This protein is essential for V(D)J recombination and DNA double strand break (DSB) repair through nonhomologous end joining (NHEJ). This protein forms a complex with the X ray repair cross complementing protein 4 (XRCC4), and further interacts with the DNA dependent protein kinase (DNA PK). Both XRCC4 and