HXB7 Polyclonal Antibody, 100ul Site-directed Mutagenesis In the nucleus

In the nucleus

GPR116 is a gene on chromosome 6p12

It is a neural recognition molecule that may be involved in signal transduction pathways

The encoded protein contains a basic-helix-loop-helix domain protein dimerization domain as well as a domain found in proteins in signal transduction pathways which respond to oxygen levels

Alternativley spliced transcript variants encoding different isoforms have been identified in this gene

HXB7 Polyclonal Antibody, 100ul Site-directed Mutagenesis In the nucleusThis gene is a member of the Antp homeobox family and encodes a protein with a homeobox DNA binding domain. It is included in a cluster of homeobox B genes located on chromosome 17. The encoded nuclear protein functions as a sequence specific transcription factor that is involved in cell proliferation and differentiation. Increased expression of this gene is associated with some cases of melanoma and ovarian carcinoma.