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IL-2R Alpha Polyclonal Antibody, 50ul[BT-AP04487] Apoptosis & Autophagy the N-terminal fragment (MST3/N) translocates

SKU: 20881296403

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IL-2R Alpha Polyclonal Antibody, 50ul[BT-AP04487] Apoptosis & Autophagy the N-terminal fragment (MST3/N) translocatesThe interleukin 2 (IL2) receptor alpha (IL2RA) and beta (IL2RB) chains, together with the common gamma chain (IL2RG), constitute the high affinity IL2 receptor. Homodimeric alpha chains (IL2RA) result in low affinity receptor, while homodimeric beta (IL2RB) chains produce a medium affinity receptor. Normally an integral membrane protein, soluble IL2RA has been isolated and determined to result from extracellular proteolyisis. Alternately spliced IL2RA

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Description

the N-terminal fragment (MST3/N) translocates to the nucleus and promotes programmed cells death

is a major repressor of this gene

AKAP1 encodes a member of the AKAP family

The protein localizes to the axial elements of chromosomes during meiosis in both oocytes and spermatocytes

it acts as a co-activator for several transcription factors

IL-2R Alpha Polyclonal Antibody, 50ul[BT-AP04487] Apoptosis & Autophagy the N-terminal fragment (MST3/N) translocatesThe interleukin 2 (IL2) receptor alpha (IL2RA) and beta (IL2RB) chains, together with the common gamma chain (IL2RG), constitute the high affinity IL2 receptor. Homodimeric alpha chains (IL2RA) result in low affinity receptor, while homodimeric beta (IL2RB) chains produce a medium affinity receptor. Normally an integral membrane protein, soluble IL2RA has been isolated and determined to result from extracellular proteolyisis. Alternately spliced IL2RA

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