Lck BP-1 Polyclonal Antibody, 100ul Drug Development and Evaluation ZMIZ2 and ZMIZ1 (MIM 607159)

ZMIZ2 and ZMIZ1 (MIM 607159) are members of a PIAS (see MIM 603566)-like family of proteins that interact with nuclear hormone receptors

Zyxin is a zinc-binding phosphoprotein that concentrates at focal adhesions and along the actin cytoskeleton

The DNA-binding activity may reside exclusively on the 70 kDa subunit

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A similar protein in Rat appears to bind the large subunit of RNA polymerase II and provide a link between transcription and pre-mRNA splicing

Lck BP-1 Polyclonal Antibody, 100ul Drug Development and Evaluation ZMIZ2 and ZMIZ1 (MIM 607159)Substrate of the antigen receptor coupled tyrosine kinase. Plays a role in antigen receptor signaling for both clonal expansion and deletion in lymphoid cells. May also be involved in the regulation of gene expression.