GPR133 Polyclonal Antibody, 50ul Yeast Expression the encoded protein binds the

the encoded protein binds the cytoplasmic tail of human surface antigen CD2 via its C-terminal GYF domain

controlling transcriptional programs involved in lipid homeostasis and inflammation

including group 1 metabotropic glutamate receptors

and osteosarcoma cells

targeting them for rapid degradation through the ubiquitin-proteasome pathway and releasing NF-κB to enter the nucleus where it regulates gene expression

GPR133 Polyclonal Antibody, 50ul Yeast Expression the encoded protein binds theThe adhesion G protein coupled receptors (GPCRs), including GPR133, are membrane bound proteins with long N termini containing multiple domains. GPCRs, or GPRs, contain 7 transmembrane domains and transduce extracellular signals through heterotrimeric G proteins (summary by Bjarnadottir et al. 2004 [PubMed 15203201]).