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GMIP Rabbit Polyclonal Antibody, 20ul Protein Modification Cleavage stimulation factor subunit 2

SKU: 19235804274

4.4
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GMIP Rabbit Polyclonal Antibody, 20ul Protein Modification Cleavage stimulation factor subunit 2This gene encodes a member of the ARHGAP family of Rho Rac Cdc42 like GTPase activating proteins. The encoded protein interacts with the Ras related protein Gem through its N terminal domain. Separately it interacts with RhoA through a RhoGAP domain and stimulates RhoA dependent GTPase activity. Alternative splicing results in multiple transcript variants.

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Description

Cleavage stimulation factor subunit 2 is a member of the cleavage stimulation factor (CSTF) complex that is involved in the 3' end cleavage and polyadenylation of pre-mRNAs

The protein encoded by KRT37 (keratin 37) is a member of the keratin gene family

ARHGAP22 (Rho GTPase activating protein 22) encodes a member of the GTPase activating protein family which activates a GTPase belonging to the RAS superfamily of small GTP-binding proteins

and is known to be an important co-receptor for macrophage-tropic virus

Studies in mice and human suggest that STEAP4 maybe involved in adipocyte development and metabolism

GMIP Rabbit Polyclonal Antibody, 20ul Protein Modification Cleavage stimulation factor subunit 2This gene encodes a member of the ARHGAP family of Rho Rac Cdc42 like GTPase activating proteins. The encoded protein interacts with the Ras related protein Gem through its N terminal domain. Separately it interacts with RhoA through a RhoGAP domain and stimulates RhoA dependent GTPase activity. Alternative splicing results in multiple transcript variants.

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