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UBP26 Polyclonal Antibody, 20ul PCR Series The proteins of this family

SKU: 19182897817

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UBP26 Polyclonal Antibody, 20ul PCR Series The proteins of this familyThis gene encodes a member of the ubiquitin specific processing (UBP) family of proteases and is a deubiquitinating enzyme (DUB) with His and Cys domains. It is specifically expressed in testis tissue. Mutations in this gene have been associated with Sertoli cell only syndrome and male infertility.

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Description

The proteins of this family form hetero- or homodimers and act as anti- and pro-apoptotic regulators that are involved in a wide variety of cellular activities such as embryonic development

The encoded protein itself is found in a complex of proteins

and data from animal models shows that this protein may have anti-fibrotic and cardioprotective effects

Mutations in RAF1 are associated with Noonan syndrome 5 and LEOPARD syndrome 2

Involved in nucleolar processing of pre-18S ribosomal RNA

UBP26 Polyclonal Antibody, 20ul PCR Series The proteins of this familyThis gene encodes a member of the ubiquitin specific processing (UBP) family of proteases and is a deubiquitinating enzyme (DUB) with His and Cys domains. It is specifically expressed in testis tissue. Mutations in this gene have been associated with Sertoli cell only syndrome and male infertility.

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