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Fibulin-3 Polyclonal Antibody, 100ul Thermal Control suggesting that down-regulation is the

SKU: 19133401483

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Fibulin-3 Polyclonal Antibody, 100ul Thermal Control suggesting that down-regulation is theEFEMP1 encodes a member of the fibulin family of extracellular matrix glycoproteins. Like all members of this family, the EGF containing fibulin like extracellular matrix protein 1 contains tandemly repeated epidermal growth factor like repeats followed by a C terminus fibulin type domain. This gene is upregulated in malignant gliomas and may play a role in the aggressive nature of these tumors. Mutations in this gene are associated with Doyne

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Description

suggesting that down-regulation is the result of methylation of the gene

Multiple alternatively spliced transcript variants have been observed that encode distinct proteins

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The protein encoded by this gene belongs to the otogelin family

This gene encodes the theta subunit of the GABA A receptor

Fibulin-3 Polyclonal Antibody, 100ul Thermal Control suggesting that down-regulation is theEFEMP1 encodes a member of the fibulin family of extracellular matrix glycoproteins. Like all members of this family, the EGF containing fibulin like extracellular matrix protein 1 contains tandemly repeated epidermal growth factor like repeats followed by a C terminus fibulin type domain. This gene is upregulated in malignant gliomas and may play a role in the aggressive nature of these tumors. Mutations in this gene are associated with Doyne

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