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HIF-1 Alpha Polyclonal Antibody, 50ul[BT-AP03965] Molecular Sciences Alternative splicing results in multiple

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HIF-1 Alpha Polyclonal Antibody, 50ul[BT-AP03965] Molecular Sciences Alternative splicing results in multipleHIF1A encodes the alpha subunit of transcription factor hypoxia inducible factor 1 (HIF 1), which is a heterodimer composed of an alpha and a beta subunit. HIF 1 functions as a master regulator of cellular and systemic homeostatic response to hypoxia by activating transcription of many genes, including those involved in energy metabolism, angiogenesis, apoptosis, and other genes whose protein products increase oxygen delivery or facilitate metabolic

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Description

Alternative splicing results in multiple transcript variants encoding proteins with distinct C-termini

Component of the AP-1 transcription factor that represses transactivation mediated by the Jun family of proteins

In combination with the beta 7 integrin| this protein forms the E-cadherin binding integrin known as the human mucosal lymphocyte-1 antigen

Annexin A1 inhibits phospholipase A2 and has anti-inflammatory activity

tissue specificity:Expressed in brain and leukocytes

HIF-1 Alpha Polyclonal Antibody, 50ul[BT-AP03965] Molecular Sciences Alternative splicing results in multipleHIF1A encodes the alpha subunit of transcription factor hypoxia inducible factor 1 (HIF 1), which is a heterodimer composed of an alpha and a beta subunit. HIF 1 functions as a master regulator of cellular and systemic homeostatic response to hypoxia by activating transcription of many genes, including those involved in energy metabolism, angiogenesis, apoptosis, and other genes whose protein products increase oxygen delivery or facilitate metabolic

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