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IL-4R alpha(Phospho Tyr497) Polyclonal Antibody, 50ul Nucleic Acid Extraction Mutations in this gene have

SKU: 18475401390

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IL-4R alpha(Phospho Tyr497) Polyclonal Antibody, 50ul Nucleic Acid Extraction Mutations in this gene haveThis gene encodes the alpha chain of the interleukin 4 receptor, a type I transmembrane protein that can bind interleukin 4 and interleukin 13 to regulate IgE production. The encoded protein also can bind interleukin 4 to promote differentiation of Th2 cells. A soluble form of the encoded protein can be produced by proteolysis of the membrane bound protein, and this soluble form can inhibit IL4 mediated cell proliferation and IL5 upregulation by T

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Description

Mutations in this gene have been associated with optic nerve hypoplasia and with syndromic microphthalmia

in which increased plasma cholesterol and triglycerides are the consequence of impaired clearance of chylomicron and VLDL remnants

This gene is one member of a family of sulfate/anion transporter genes

UBE4B encodes an additional conjugation factor

This gene is a member of the MER/AXL/TYRO3 receptor kinase family and encodes a transmembrane protein with two fibronectin type-III domains

IL-4R alpha(Phospho Tyr497) Polyclonal Antibody, 50ul Nucleic Acid Extraction Mutations in this gene haveThis gene encodes the alpha chain of the interleukin 4 receptor, a type I transmembrane protein that can bind interleukin 4 and interleukin 13 to regulate IgE production. The encoded protein also can bind interleukin 4 to promote differentiation of Th2 cells. A soluble form of the encoded protein can be produced by proteolysis of the membrane bound protein, and this soluble form can inhibit IL4 mediated cell proliferation and IL5 upregulation by T

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