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Bmi-1 Rabbit Polyclonal Antibody(F270), 20ul Mechanical Pipette Mutations in this gene are

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Bmi-1 Rabbit Polyclonal Antibody(F270), 20ul Mechanical Pipette Mutations in this gene areThis gene encodes a ring finger protein that is major component of the polycomb group complex 1 (PRC1). This complex functions through chromatin remodeling as an essential epigenetic repressor of multiple regulatory genes involved in embryonic development and self renewal in somatic stem cells. This protein also plays a central role in DNA damage repair. This gene is an oncogene and aberrant expression is associated with numerous cancers and is

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Description

Mutations in this gene are associated with azoospermia in males and susceptibility to pregnancy loss in females

Two alternatively spliced transcript variants encoding different isoforms of PSEN2 have been identified

It is a RNA exonuclease that binds to the 3'-end of histone mRNAs and degrades them

This enzyme| which is phosphorylated on tyrosine residues upon T-cell antigen receptor (TCR) stimulation| functions in the initial step of TCR-mediated signal transduction in combination with the Src family kinases| Lck and Fyn

7-transmembrane receptor (GPCR) superfamily

Bmi-1 Rabbit Polyclonal Antibody(F270), 20ul Mechanical Pipette Mutations in this gene areThis gene encodes a ring finger protein that is major component of the polycomb group complex 1 (PRC1). This complex functions through chromatin remodeling as an essential epigenetic repressor of multiple regulatory genes involved in embryonic development and self renewal in somatic stem cells. This protein also plays a central role in DNA damage repair. This gene is an oncogene and aberrant expression is associated with numerous cancers and is

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