AAT Polyclonal Antibody, 20ul[BT-AP00075] Subcellular Fractions have been found for YWHAE

have been found for YWHAE

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the reference genome represents the coding allele

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AAT Polyclonal Antibody, 20ul[BT-AP00075] Subcellular Fractions have been found for YWHAEAASS encodes a bifunctional enzyme (aminoadipate semialdehyde synthase) that catalyzes the first two steps in the mammalian lysine degradation pathway. The N terminal and the C terminal portions of this enzyme contain lysine ketoglutarate reductase and saccharopine dehydrogenase activity, respectively, resulting in the conversion of lysine to alpha aminoadipic semialdehyde. Mutations in AASS are associated with familial hyperlysinemia.