p300 Polyclonal Antibody, 100ul[BT-AP06775] Site-directed Mutagenesis and has been linked to

and has been linked to primary microcephaly and Alzheimer's disease

Mutations in this gene have been associated with bone marrow failure syndrome 2

The protein encoded by PLN (phospholamban)is found as a pentamer and is a major substrate for the cAMP-dependent protein kinase in cardiac muscle

with physiological effects including regulation of metabolic rate

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p300 Polyclonal Antibody, 100ul[BT-AP06775] Site-directed Mutagenesis and has been linked toEP300 encodes the adenovirus E1A associated cellular p300 transcriptional co activator protein. It functions as histone acetyltransferase that regulates transcription via chromatin remodeling and is important in the processes of cell proliferation and differentiation. It mediates cAMP gene regulation by binding specifically to phosphorylated CREB protein. EP300 has also been identified as a co activator of HIF1A (hypoxia inducible factor 1 alpha), and