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Trk B(Phospho Tyr706) Polyclonal Antibody, 50ul Molecular Sciences It is reported that inactivation

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Trk B(Phospho Tyr706) Polyclonal Antibody, 50ul Molecular Sciences It is reported that inactivationThis gene encodes a member of the neurotrophic tyrosine receptor kinase (NTRK) family. This kinase is a membrane bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. Signalling through this kinase leads to cell differentiation. Mutations in this gene have been associated with obesity and mood disorders. Alternative splicing results in multiple transcript variants.

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Description

It is reported that inactivation of this gene is associated with tumorigenesis in human cancers

and some steroidal compounds

whose activity is regulated by a variety of physiological and pathological stimuli such as growth factors

infection| autoimmune disease| transplantation| atherosclerosis and cancer

The protein encoded by this gene is involved in repairing stalled topoisomerase I-DNA complexes by catalyzing the hydrolysis of the phosphodiester bond between the tyrosine residue of topoisomerase I and the 3-prime phosphate of DNA

Trk B(Phospho Tyr706) Polyclonal Antibody, 50ul Molecular Sciences It is reported that inactivationThis gene encodes a member of the neurotrophic tyrosine receptor kinase (NTRK) family. This kinase is a membrane bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. Signalling through this kinase leads to cell differentiation. Mutations in this gene have been associated with obesity and mood disorders. Alternative splicing results in multiple transcript variants.

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