BACD3 Rabbit Polyclonal Antibody, 20ul Cell Function Analysis Activation of the encoded receptor

Activation of the encoded receptor results in contraction and proliferation of bronchial smooth muscle cells

Increased transcriptional expression of POT1 is associated with stomach carcinogenesis and its progression

The import of proteins containing a nuclear localization signal (NLS) requires the NLS import receptor| a heterodimer of importin alpha and beta subunits also known as karyopherins

and is involved in clathrin-mediated endocytosis and other vesicular trafficking processes

AKR1C3 shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14

BACD3 Rabbit Polyclonal Antibody, 20ul Cell Function Analysis Activation of the encoded receptorThe protein encoded by this gene binds proliferating cell nuclear antigen (PCNA) and may be involved in DNA synthesis and cell proliferation. In addition, the encoded protein may be a tumor suppressor. Several protein coding and non protein coding transcript variants have been found for this gene.