Parkin Polyclonal Antibody, 50ul Endonucleases & Exonucleases The protein may also play

The protein may also play a role in the morphological organization of liver and intestine

and induces apoptosis in transfected cells

and calcium

Gene Ontology (GO) annotations related to this gene include chromatin binding and RNA polymerase II transcription corepressor activity

a multiprotein coactivator of RNA transcription that interacts with DNA-bound transcriptional activators

Parkin Polyclonal Antibody, 50ul Endonucleases & Exonucleases The protein may also playThe precise function of PARK2 is unknown; however, the encoded protein is a component of a multiprotein E3 ubiquitin ligase complex that mediates the targeting of substrate proteins for proteasomal degradation. Mutations in PARK2 are known to cause Parkinson disease and autosomal recessive juvenile Parkinson disease. Alternative splicing of PARK2 produces multiple transcript variants encoding distinct isoforms. Additional splice variants of PARK2 have