p53 Rabbit Polyclonal Antibody, 50ul[BT-AP11718] In vitro Assessment knockdown of the gene in

knockdown of the gene in cell culture results in an increase in amyloid pre

Mutations in this gene cause Charcot-Marie-Tooth disease| type 2A1

cell metabolism

a myosin phosphatase targeting (MYPT) subunit

The encoded protein is localized to the nucleolus where it functions in chromatin remodeling and as an inhibitor of cell-cycle progression

p53 Rabbit Polyclonal Antibody, 50ul[BT-AP11718] In vitro Assessment knockdown of the gene inThis gene encodes a tumor suppressor protein containing transcriptional activation DNA binding and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes thereby inducing cell cycle arrest apoptosis senescence DNA repair or changes in metabolism. Mutations in this gene are associated with a variety of human cancers including hereditary cancers such as Li Fraumeni syndrome. Alternative