TRAIP Rabbit Polyclonal Antibody, 20ul Aspirating Pipets development and immune responses

development and immune responses

It plays a key role in cellular antiviral response by negatively regulating the interferon response factor 3-mediated expression of interferon beta

Phosphorylation of the encoded protein has been shown to have an inhibitory effect on its chaperone function

miscellaneous:Enzyme activity requires the presence of both kinase domains

Different members of the subfamily can readily form heterodimers

TRAIP Rabbit Polyclonal Antibody, 20ul Aspirating Pipets development and immune responsesThis gene encodes a protein that contains an N terminal RING finger motif and a putative coiled coil domain. A similar murine protein interacts with TNFR associated factor 1 (TRAF1) TNFR associated factor 2 (TRAF2) and cylindromatosis. The interaction with TRAF2 inhibits TRAF2 mediated nuclear factor kappa B subunit 1 activation that is required for cell activation and protection against apoptosis.