AIF1 Polyclonal Antibody, 100ul Site-directed Mutagenesis The up-regulation of this gene

The up-regulation of this gene is found to be associated with a number of infectious diseases

This protein also associates with condensed chromosome arms and may be involved in maintaining chromosome integrity during mitosis

Mutations in this gene as well as recurrent translocations involving this gene have also been observed in some tumors

This enzyme may be involved in the processing of bacterial peptides and endogenous proteins for MHC class II presentation in the lysosomal/endosomal systems

PTM:Phosphorylated upon DNA damage

AIF1 Polyclonal Antibody, 100ul Site-directed Mutagenesis The up-regulation of this geneThis gene encodes a protein that binds actin and calcium. This gene is induced by cytokines and interferon and may promote macrophage activation and growth of vascular smooth muscle cells and T lymphocytes. Polymorphisms in this gene may be associated with systemic sclerosis. Alternative splicing results in multiple transcript variants, but the full length and coding nature of some of these variants is not certain.