PAR14 Polyclonal Antibody, 100ul Measuring Instruments and PIASx interact with and

and PIASx interact with and repress Stat1

since both contain an extracellular region with a 2-domain structure composed of an immunoglobulin-like domain and a cytokine receptor-like domain

Ser-376 and Ser-212 are autophosphorylated by the C-terminal kinase domain

The protein plays a role in moving the spindle assembly checkpoint (SAC) from kinetochores to spindle poles

Multiple transcript variants encoding different proteins have been found for this gene

PAR14 Polyclonal Antibody, 100ul Measuring Instruments and PIASx interact with andThis gene encodes a member of the poly(ADP ribose) polymerase (PARP) protein family. The encoded anti apoptotic protein may regulate aerobic glycolysis and promote survival of cancer cells. Increased expression of this gene has been reported in a variety of tumor types.