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AP-1 (Acetyl Lys271) Polyclonal Antibody, 100ul Adeno-associated Virus Packaging This gene is one of

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AP-1 (Acetyl Lys271) Polyclonal Antibody, 100ul Adeno-associated Virus Packaging This gene is one ofJUN is the putative transforming gene of avian sarcoma virus 17. It encodes a protein (Jun proto oncogene, AP 1 transcription factor subunit) which is highly similar to the viral protein, and which interacts directly with specific target DNA sequences to regulate gene expression. JUN is intronless and is mapped to 1p32 p31, a chromosomal region involved in both translocations and deletions in human malignancies.

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Description

This gene is one of the leukocyte receptor genes that form a gene cluster on the chromosomal region 19q13

ABC proteins transport various molecules across extra-and intra-cellular membranes

suggesting a possible role for CTSV in tumor processes

The protein encoded by this gene shares a critical BH3 domain with other death-promoting proteins

The protein is an E3 ligase and is involved in ubiquitination and proteasome-mediated degradation of specific proteins

AP-1 (Acetyl Lys271) Polyclonal Antibody, 100ul Adeno-associated Virus Packaging This gene is one ofJUN is the putative transforming gene of avian sarcoma virus 17. It encodes a protein (Jun proto oncogene, AP 1 transcription factor subunit) which is highly similar to the viral protein, and which interacts directly with specific target DNA sequences to regulate gene expression. JUN is intronless and is mapped to 1p32 p31, a chromosomal region involved in both translocations and deletions in human malignancies.

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