ADCYA Rabbit Polyclonal Antibody, 20ul Contamination Detection & Removal Alternative splicing of this gene

Alternative splicing of this gene results in three tissue-specific forms of glucokinase

the catalytic N-terminal| and the C-terminal which is involved in substrate specificity and in binding TIMP (tissue inhibitor of metalloproteinases)

This gene encodes a nucleolar protein that localizes to punctate subnuclear structures that occur close to splicing speckles

Multiple alternatively spliced transcript variants that encode different protein isoforms have been observed in this gene

Alternativley spliced transcript variants encoding different isoforms have been identified in this gene

ADCYA Rabbit Polyclonal Antibody, 20ul Contamination Detection & Removal Alternative splicing of this geneThe protein encoded by this gene belongs to a distinct class of adenylyl cyclases that is soluble and insensitive to G protein or forskolin regulation. Activity of this protein is regulated by bicarbonate. Variation at this gene has been observed in patients with absorptive hypercalciuria. Alternatively spliced transcript variants encoding different isoforms have been observed. There is a pseudogene of this gene on chromosome 6.