MEK-6(Phospho Ser207) Polyclonal Antibody, 50ul Diagnostic Probes & Oligos Alternatively spliced transcript variants encoding

Alternatively spliced transcript variants encoding multiple isoforms have been observed for PIAS2

Acts as a negative regulator of the Toll-like and IL-1R receptor signaling pathways

The protein encoded by ERF binds to the ETS2 promoter and is a strong repressor of ETS2 transcription

Alternatively spliced transcript variants encoding distinct isoforms have been described

In mice| the disabled-1 gene plays a central role in brain development| directing the migration of cortical neurons past previously formed neurons to reach their proper layer

MEK-6(Phospho Ser207) Polyclonal Antibody, 50ul Diagnostic Probes & Oligos Alternatively spliced transcript variants encodingThis gene encodes a member of the dual specificity protein kinase family, which functions as a mitogen activated protein (MAP) kinase kinase. MAP kinases, also known as extracellular signal regulated kinases (ERKs), act as an integration point for multiple biochemical signals. This protein phosphorylates and activates p38 MAP kinase in response to inflammatory cytokines or environmental stress. As an essential component of p38 MAP kinase mediated