NFκB-p105(Phospho Ser893) Polyclonal Antibody, 100ul Vector Construction Involved in the proper sorting

Involved in the proper sorting of TYRP1

The leukocyte immunoglobulin like receptor B5 belongs to the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains

Gene Ontology (GO) annotations related to this gene include G-protein coupled receptor activity and neuropeptide Y receptor activity

A mutation in this gene has been correlated with T-cell immunodeficiency

The encoded protein facilitates translocation of a functional guanine nucleotide exchange factor (GEF) complex from the cytoplasm to the plasma membrane where ras-related C3 botulinum toxin substrate 1 is activated to promote lamellipodium formation and cell migration

NFκB-p105(Phospho Ser893) Polyclonal Antibody, 100ul Vector Construction Involved in the proper sortingThis gene encodes a 105 kD protein which can undergo cotranslational processing by the 26S proteasome to produce a 50 kD protein. The 105 kD protein is a Rel protein specific transcription inhibitor and the 50 kD protein is a DNA binding subunit of the NF kappa B (NFKB) protein complex. NFKB is a transcription regulator that is activated by various intra and extra cellular stimuli such as cytokines oxidant free radicals ultraviolet irradiation and