CKR-5 Polyclonal Antibody, 100ul[BT-AP07729] Human Genome Knockout Libraries each with distinct biological functions

each with distinct biological functions

It encodes a protein of unknown function

Mutations in this gene can result in B cell deficiency and agammaglobulinemia

This protein is found in nuclear Gemini of Cajal bodies (gems) and in the cytoplasm

This gene encodes a 105 kD protein which can undergo cotranslational processing by the 26S proteasome to produce a 50 kD protein

CKR-5 Polyclonal Antibody, 100ul[BT-AP07729] Human Genome Knockout Libraries each with distinct biological functionsThis gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein coupled receptors. This protein is expressed by T cells and macrophages, and is known to be an important co receptor for macrophage tropic virus, including HIV, to enter host cells. Defective alleles of this gene have been associated with the HIV infection resistance. The ligands of this receptor include