TFE3 Polyclonal Antibody, 50ul Centrifuge Tube (Bottle) GPR174 (G protein-coupled receptor 174)

GPR174 (G protein-coupled receptor 174) encodes a protein belonging to the G protein-coupled receptor superfamily

It functions as the main structural component of the lattice-type cytoplasmic face of coated pits and vesicles which entrap specific macromolecules during receptor-mediated endocytosis

Involved in vesicular transport between the endoplasmic reticulum and the Golgi

It contains four active calcium-binding domains

but not STAT2 kinase

TFE3 Polyclonal Antibody, 50ul Centrifuge Tube (Bottle) GPR174 (G protein-coupled receptor 174)TFE3 (transcription factor binding to IGHM enhancer 3) encodes a basic helix loop helix domain containing transcription factor that binds MUE3 type E box sequences in the promoter of genes. The encoded protein promotes the expression of genes downstream of transforming growth factor beta (TGF beta) signaling. TFE3 may be involved in chromosomal translocations in renal cell carcinomas and other cancers, resulting in the production of fusion proteins.