Elk-1 Polyclonal Antibody, 50ul[BT-AP02911] Oligo Pool Mutations in CBX2 are also

Mutations in CBX2 are also associated with gonadal dysgenesis in humans

The protein encoded by PIGH is a subunit of the GPI N-acetylglucosaminyl (GlcNAc) transferase that transfers GlcNAc to phosphatidylinositol (PI) on the cytoplasmic side of the endoplasmic reticulum

resulting in the transcriptional activation of target genes

The encoded protein also plays a critical role in antioxidant defense by regenerating overoxidized peroxiredoxins

The protein encoded by this gene is a subunit of the multiprotein complexes PC2 and ARC/DRIP and may function as a transcriptional coactivator in RNA polymerase II transcription

Elk-1 Polyclonal Antibody, 50ul[BT-AP02911] Oligo Pool Mutations in CBX2 are alsoELK1 is a member of the Ets family of transcription factors and of the ternary complex factor (TCF) subfamily. Proteins of the TCF subfamily form a ternary complex by binding to the the serum response factor and the serum response element in the promoter of the c fos proto oncogene. The protein encoded by ELK1 is a nuclear target for the ras raf MAPK signaling cascade. ELK1 produces multiple isoforms by using alternative translational start codons and