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PI-9 Polyclonal Antibody, 100ul Aspirating Pipets Defects in this gene are

SKU: 11744956102

4.5
PLN123.75 PLN153.75

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PI-9 Polyclonal Antibody, 100ul Aspirating Pipets Defects in this gene areSERPINB9 encodes a member of the serine protease inhibitor family which are also known as serpins. The encoded protein belongs to a subfamily of intracellular serpins. Serpin family B member 9 inhibits the activity of the effector molecule granzyme B. Overexpression of serpin family B member 9 may prevent cytotoxic T lymphocytes from eliminating certain tumor cells. A pseudogene of SERPINB9 is found on chromosome 6.

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Description

Defects in this gene are associated with T cell immunodeficiency

The protein encoded by this gene is a member of the ADAM (a disintegrin and metalloproteinase) protein family

An important paralog of this gene is NXPH3

Alternate splicing results in multiple transcript variants encoding distinct isoforms

and neural tube

PI-9 Polyclonal Antibody, 100ul Aspirating Pipets Defects in this gene areSERPINB9 encodes a member of the serine protease inhibitor family which are also known as serpins. The encoded protein belongs to a subfamily of intracellular serpins. Serpin family B member 9 inhibits the activity of the effector molecule granzyme B. Overexpression of serpin family B member 9 may prevent cytotoxic T lymphocytes from eliminating certain tumor cells. A pseudogene of SERPINB9 is found on chromosome 6.

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