CLN3 Polyclonal Antibody, 50ul Centrifugal Filter PTM:Phosphorylation of Thr-35 is required

PTM:Phosphorylation of Thr-35 is required for activity

This protein is also thought to modify lipid metabolism and insulin-regulated gene expression

Mutations in TUBA1A cause lissencephaly type 3 (LIS3) - a neurological condition characterized by microcephaly

LMX1B encodes a member of LIM-homeodomain family of proteins containing two N-terminal zinc-binding LIM domains

resulting in the production of beta-factor XIIa light chain and the alpha-factor XIIa light chain becomes beta-factor XIIa heavy chain

CLN3 Polyclonal Antibody, 50ul Centrifugal Filter PTM:Phosphorylation of Thr-35 is requiredThis gene encodes a protein that is involved in lysosomal function. Mutations in this, as well as other neuronal ceroid lipofuscinosis (CLN) genes, cause neurodegenerative diseases commonly known as Batten disease or collectively known as neuronal ceroid lipofuscinoses (NCLs). Many alternatively spliced transcript variants have been found for this gene.