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MARCH2 Polyclonal Antibody, 20ul Protein Modification In experiments with non-human species

SKU: 10305469243

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MARCH2 Polyclonal Antibody, 20ul Protein Modification In experiments with non-human speciesMARCH2 (membrane associated ring CH type finger 2) is a member of the MARCH family of membrane bound E3 ubiquitin ligases. MARCH enzymes add ubiquitin (see MIM 191339) to target lysines in substrate proteins, thereby signaling their vesicular transport between membrane compartments. MARCH2 reduces surface accumulation of several glycoproteins and appears to regulate early endosome to trans Golgi network (TGN) trafficking.

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In experiments with non-human species

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Alternatively spliced transcript variants have been observed for CNOT2

MARCH2 Polyclonal Antibody, 20ul Protein Modification In experiments with non-human speciesMARCH2 (membrane associated ring CH type finger 2) is a member of the MARCH family of membrane bound E3 ubiquitin ligases. MARCH enzymes add ubiquitin (see MIM 191339) to target lysines in substrate proteins, thereby signaling their vesicular transport between membrane compartments. MARCH2 reduces surface accumulation of several glycoproteins and appears to regulate early endosome to trans Golgi network (TGN) trafficking.

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