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HMGA1 Polyclonal Antibody, 50ul Electronic Pipette tissue specificity:Isoform 3 has highest

SKU: 10190915297

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HMGA1 Polyclonal Antibody, 50ul Electronic Pipette tissue specificity:Isoform 3 has highestThis gene encodes a chromatin associated protein involved in the regulation of gene transcription, integration of retroviruses into chromosomes, and the metastatic progression of cancer cells. The encoded protein preferentially binds to the minor groove of AT rich regions in double stranded DNA. Multiple transcript variants encoding different isoforms have been found for this gene. Pseudogenes of this gene have been identified on multiple chromosomes.

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Description

tissue specificity:Isoform 3 has highest expression levels in the brain

This gene is a member of the Ig superfamily and encodes a cell surface sialoglycoprotein expressed by cytokine-activated endothelium

Overexpression of CDCA7 is found to enhance the transformation of lymphoblastoid cells

RAN is an androgen receptor (AR) coactivator that binds differentially with different lengths of polyglutamine within the androgen receptor

The encoded protein constitutes a substantial portion of lipoprotein(a) and is proteolytically cleaved

HMGA1 Polyclonal Antibody, 50ul Electronic Pipette tissue specificity:Isoform 3 has highestThis gene encodes a chromatin associated protein involved in the regulation of gene transcription, integration of retroviruses into chromosomes, and the metastatic progression of cancer cells. The encoded protein preferentially binds to the minor groove of AT rich regions in double stranded DNA. Multiple transcript variants encoding different isoforms have been found for this gene. Pseudogenes of this gene have been identified on multiple chromosomes.

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