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Stimulant laxatives such as senna or bisacodyl should be reserved for occasional use (no more than twice weekly) because regular use can train your colon to depend on them, worsening constipation long-term

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Additionally, we utilized various algorithms including reporting odds ratio (ROR), proportional reporting ratio (PRR), Bayesian confidence propagation neural network (BCPNN), and multi-item gamma Poisson shrinker (MGPS) to analyze data from the Food and Drug Administrations Adverse Event Reporting System (FAERS) regarding suspected adverse events of AP linked to GLP-1 RAs from January 2005 to September 2023