IQGAP1 Polyclonal Antibody, 50ul Cell Biology The role it plays in

The role it plays in metastasis is unclear

The read-through codon occurs primarily in individuals of African descent and carriers have endotoxin hypo-responsiveness and an increased susceptibility to severe sepsis

reduces the recruitment of inhibitor-of-apoptosis proteins (IAPs) by TRAF2

Involved in the activation of MAP kinases

and no expression in kidney

IQGAP1 Polyclonal Antibody, 50ul Cell Biology The role it plays inIQGAP1 encodes a member of the IQGAP family. Ras GTPase activating like protein IQGAP1 contains four IQ domains, one calponin homology domain, one Ras GAP domain and one WW domain. It interacts with components of the cytoskeleton, with cell adhesion molecules, and with several signaling molecules to regulate cell morphology and motility. Expression of the protein is upregulated by gene amplification in two gastric cancer cell lines.